Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis.
نویسندگان
چکیده
The screening of a diversity-oriented synthesis library followed by structure-activity relationship investigations have led to the discovery of an anti-MRSA agent which operates as an inhibitor of Staphylococcus aureus dihydrofolate reductase.
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ورودعنوان ژورنال:
- Chemical communications
دوره 40 شماره
صفحات -
تاریخ انتشار 2008